Connect with us

Hi, what are you looking for?

Jewish Business News


Unexplained Repeated Pregnancy Loss is Associated with Brain Responses to Men’s Body-Odor

New research at the Weizmann Institute of Science suggests that the odors are a sort of body language – one that may affect our relationships more than we realize.

Women who suffer from a condition known as unexplained repeated pregnancy loss (uRPL) process messages concerning male body odor – especially their husband’s – in a different way than other women. These findings may point to new directions in the search for causes and prevention of this poorly understood disorder, new research by Prof. Noam Sobel and his team from the Neurobiology Department at the Weizmann Institute of Science suggests.

In 1959, Hilda Bruce discovered that when pregnant mice are exposed to the body-odor of a male who was not the father they will almost always abort. Sobel and his team thought that some cases of uRPL could be related to a human variation on the Bruce effect.

Please help us out :
Will you offer us a hand? Every gift, regardless of size, fuels our future.
Your critical contribution enables us to maintain our independence from shareholders or wealthy owners, allowing us to keep up reporting without bias. It means we can continue to make Jewish Business News available to everyone.
You can support us for as little as $1 via PayPal at
Thank you.

Why this occurs is not fully understood, but the common ratio is that the female “opt for ” to abort because the chemical message is that a new “more fit” male is in town.

It is estimated that 50% of all human conceptions and some 15% of documented human pregnancies, end in spontaneous miscarriage. Ethical considerations prevented the researchers from repeating the Bruce experiments in humans.

Therefore the study, which was published in eLife, sought circumstantial evidence.

For the Bruce effect to occur in mice, the female must remember the body-odor of the fathering male. To test for this in humans, the researchers presented participants with three odorants: one extracted from a t-shirt worn by their spouse, and two from t-shirts worn by non-spouse men. They found that women with uRPL were able to identify their spouse by smell, while the control women could not.

When retested with ordinary odorants to see if those with uRPL simply had a better sense of smell overall, they tested only marginally better. The ability of uRPL women to identify their spouse by smell was remarkable: In another part of the experiment, in which the women did not know what odors they would be smelling, “several of these women said ‘oh, my husband’s in here’,” says research student Reut Weissgross, who co-lead the study. This never happened once with the control women.

Further testing suggested that these women are not just better at picking out the smell of their spouse, they may experience men’s body-odor in a different way altogether.
When asked to rate men’s body-odors on various scales, including ranking them by standard scales for pleasantness and intensity, but also by such factors as fertility or sex appeal, the uRPL-affected women were unique in the way they described and graded the smells, and significantly different from control women in their answers.

Structural imaging revealed that women with uRPL have smaller olfactory bulbs; these are the initial brain-relay for smell.

Functional imaging, found an increased response to men’s body-odors in the hypothalamus of women with uRPL.

The hypothalamus is a brain region that participates, among other things, in coordinating pregnancy and overall hormonal regulation.

Sobel cautions: “Our findings do not prove in any way that the olfactory system, or body-odors, cause miscarriage. But our findings do point to a novel and potentially important direction for research in this poorly condition.”



You May Also Like

World News

In the 15th Nov 2015 edition of Israel’s good news, the highlights include:   ·         A new Israeli treatment brings hope to relapsed leukemia...


The Movie The Professional is what made Natalie Portman a Lolita.


After two decades without a rating system in Israel, at the end of 2012 an international tender for hotel rating was published.  Invited to place bids...

VC, Investments

You may not become a millionaire, but there is a lot to learn from George Soros.