A new study discovers a new mechanism for activating the immune system against cancer cells. The mechanism allows immune cells to detect and destroy cancer cells in particular in cases of lung cancer and melanoma and melanoma.
The study led by Professor Nick Haining, of Harvard Medical School, and by Israeli Prof. Erez Levanon of Life Sciences at Bar-Ilan University, published in the journal Nature.
Will you offer us a hand? Every gift, regardless of size, fuels our future.
Your critical contribution enables us to maintain our independence from shareholders or wealthy owners, allowing us to keep up reporting without bias. It means we can continue to make Jewish Business News available to everyone.
You can support us for as little as $1 via PayPal at email@example.com.
The team has discovered that when inhibiting this mechanism, the immune system can be harnessed to fight cancer cells in a, particularly efficient manner. “We found that if the mechanism is blocked, the immune system is much more sensitive,” Levanon said. “When the mechanism is deactivated, the immune system becomes much more aggressive against the tumor cells.”
The study focused on a mechanism that routinely serves the cell by marking human virus-like-genes in order to avoid identifying them as viruses. Recent years have seen the development of cancer drugs developed with blocks proteins that inhibit immune activity against several tumor types.
The 2018 Nobel Prize in Medicine was awarded to James Allison and Tasuku Honjo, for discovering the key genes of this mechanism.