Published On: Thu, Aug 18th, 2016

Israel’s Nutrina Raises $30 Million for Infant oral Insulin Treatment

The Israeli company is developing a proprietary oral insulin for intestinal malabsorption in preterm newborns and Short Bowel Syndrome in infants.

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Israel-based Nutrinia, Ltd. a developer a proprietary oral formulation of insulin for newborns and Short Bowel Syndrome (SBS) in infants, today announced the closing of a $30 million Series D to fund two pivotal trials for registration.

TPG Biotech led the round with participation from other investors including H.I.G. BioHealth Partners, WuXi Healthcare Ventures, OrbiMed and Pontifax.


Nutrinia will use the proceeds to initiate two pivotal trials for registration in separate indications related to acceleration of gut maturation and adaptation: intestinal malabsorption in preterm newborns born between 26 and 32 weeks’ gestational age, and infants with SBS who are under 12 months old.

Nutrinia was founded in 2003 by Professor Naim Shehadeh head of Pediatric Diabetes Clinic at the Rambam Medical Center in Haifa, at the NGT incubator in Nazareth, which was supported by the Jacobs family, who invested in the company’s earlier investment round along with Maabarot

Nutrinia CEO Miki Olshansky said, “We are beginning two trials in the US and Europe that will provide robust data as to the safety and efficacy of our proprietary oral formulation of insulin, and if successful, provide a direct path to registration. These are orphan indications that affect fragile populations with high levels of unmet medical need.”

“The biological rationale for Nutrinia’s product is strong and the company’s preclinical data and outcomes of multiple previous clinical trials are compelling, ” said Eran Nadav, Ph.D., Partner and Managing Director at TPG Biotech. “We believe that neonatology, and specifically the NICU, are areas that deserve particular therapeutic development focus, and we are pleased to support Nutrinia’s efforts.”

With this investment, Dr. Nadav will join Nutrinia’s Board of Directors, as will Aaron Davidson, Co-head and Managing Director of H.I.G. BioHealth Partners.


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